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Scientific Publication
STX-1, a first-in-class ADC targeting DPP4 protein, acts as an anticancer andsenolytic treatment
Author Block: Benjamin Le Calvé, Delphine Dayde, Grégoire Jouffroy, Omayma Asbai, Virginie Lelarge, Justine Choeur, Thierry Mathieu, Florence Lhospice and Eric Angevin Starkage Therapeutics, Lille, France, Gustave Roussy, Villejuif, France Download PDF by clicking the image Abstract: Antibody-drug conjugates (ADCs) are innovative cancer therapies which, unlike conventional chemotherapies, enhance the anti-tumor effect while limiting adverse effects. However, it is necessary t
StarkAge
Jul 312 min read
Treatment-induced senescence in metastatic colorectal adenocarcinomas: implications for single-cell biology and therapeutic intervention.
Author Block: Antoine Hollebecque, Marine Aglave, Mohamed-Amine Bani, Trang Nguyen, Ludovic Bigot, Thierry Mathieu, Florence Lhospice, Benjamin Le Calvé, Eric Angevin Gustave Roussy, Villejuif, France, Starkage Therapeutics, Lille, France Download PDF HD by clicking the image Abstract: In cancers, the harmful effect of senescence is now well recognized and mediated by the local production of pro-inflammatory cytokines, soluble immunosuppressive factors and metalloproteinases
StarkAge
Jul 312 min read
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